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Aldolase B attenuates clear cell renal cell carcinoma progression by inhibiting CtBP2
《医学前沿(英文)》 2023年 第17卷 第3期 页码 503-517 doi: 10.1007/s11684-022-0947-9
CAR T-cell immunotherapy: a powerful weapon for fighting hematological B-cell malignancies
《医学前沿(英文)》 2021年 第15卷 第6期 页码 783-804 doi: 10.1007/s11684-021-0904-z
Chinese expert consensus on oral drugs for the treatment of mature B-cell lymphomas (2020 edition)
《医学前沿(英文)》 2022年 第16卷 第5期 页码 815-826 doi: 10.1007/s11684-021-0891-0
关键词: B-cell lymphoma oral drug targeted therapy immunotherapy COVID-19 pandemic
《医学前沿(英文)》 2022年 第16卷 第2期 页码 285-294 doi: 10.1007/s11684-021-0843-8
关键词: CAR-T cell therapy refractory diffuse large B-cell lymphoma cytokine release syndrome dose-limiting toxicity
《医学前沿(英文)》 2023年 第17卷 第4期 页码 747-757 doi: 10.1007/s11684-022-0954-x
关键词: COVID-19 convalescent SARS-CoV-2 inactivated vaccination neutralizing antibody B cell response
《医学前沿(英文)》 2023年 第17卷 第4期 页码 699-713 doi: 10.1007/s11684-022-0972-8
关键词: anti-CD19 chimeric antigen receptor T immunotherapy diffuse large B cell lymphoma tumor microenvironment tumor-associated macrophage metabolism
FAN Xiaodong, HAN Ruifa
《医学前沿(英文)》 2007年 第1卷 第4期 页码 377-380 doi: 10.1007/s11684-007-0073-8
《医学前沿(英文)》 2022年 第16卷 第1期 页码 139-149 doi: 10.1007/s11684-021-0835-8
关键词: B-cell acute lymphoblastic leukemia bispecific antibody trispecific antibody CD19 CD20
Inhibition of NF-kappa B can enhance Fas-mediated apoptosis in leukemia cell line HL-60
Li WANG, Shi ZHAO, Hong-Xiang WANG, Ping ZOU
《医学前沿(英文)》 2010年 第4卷 第3期 页码 323-328 doi: 10.1007/s11684-010-0026-5
关键词: nuclear factor-kappa B Fas/FasL system HL-60 Bay 11-7082
A facile synthesis of high activity cube-like Pt/carbon composites for fuel cell application
Reza B. MOGHADDAM, Samaneh SHAHGALDI, Xianguo LI
《能源前沿(英文)》 2017年 第11卷 第3期 页码 245-253 doi: 10.1007/s11708-017-0492-4
关键词: synthesis cube-like Pt Pt/C composite catalyst impedance
Hepatitis B virus X protein upregulates tumor necrosis factor-α expression of rat mesangial cell
Hong-Zhu LU MD, Dan LIU BM, Qi-Hong FAN BM, Jian-Hua ZHOU MD,
《医学前沿(英文)》 2010年 第4卷 第1期 页码 106-111 doi: 10.1007/s11684-010-0004-y
关键词: hepatitis B virus X gene glomerular mesangial cell line extracellular regulated protein kinases tumor necrosis factor-α
Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia
Jianfeng Li, Yuting Dai, Liang Wu, Ming Zhang, Wen Ouyang, Jinyan Huang, Saijuan Chen
《医学前沿(英文)》 2021年 第15卷 第3期 页码 347-371 doi: 10.1007/s11684-020-0821-6
关键词: BCP-ALL subtypes translocation aneuploidy sequence mutations
Yiwen Cao, Zhenhua Liu, Wen Wu, Ying Qian, Qin Shi, Rong Shen, Binshen Ouyang, Pengpeng Xu, Shu Cheng, Jin Ye, Yiming Lu, Chaofu Wang, Chengde Yang, Li Wang, Weili Zhao
《医学前沿(英文)》 2019年 第13卷 第1期 页码 94-103 doi: 10.1007/s11684-019-0680-1
Autoimmune diseases (ADs) increase the risk of non-Hodgkin’s lymphoma and contribute to poor prognosis of patients. However, the association between immunologic markers and clinical outcome has rarely been investigated. This study aims to analyze the prognostic value of pretreatment immunologic markers in newly diagnosed patients with diffuse large B-cell lymphoma (DLBCL). We retrospectively reviewed the data on 502 patients with DLBCL treated in our institution from January 2013 to March 2018. Survival functions were estimated using Kaplan–Meier method and Cox regression model. The 3-year progression free survival (PFS) and overall survival (OS) rates were 70.2% and 80.9%, respectively, and the complete remission (CR) rate was 78.1%. Among the patients, those with multiple (≥3) abnormal immunologic markers had significantly shorter 3-year PFS (52.7% vs. 77.3%, P<0.001) and OS (68.5% vs. 85.8%, P=0.001) than those without multiple abnormal immunologic markers. Multivariate analysis revealed that the presence of multiple abnormal immunologic markers and the elevated serum levels of lactate dehydrogenase were the independent adverse prognostic factors for PFS (P=0.008, P<0.001) and OS (P=0.003, P<0.001). Meanwhile, advanced Ann Arbor stage was an independent adverse prognostic factor for PFS (P=0.001) and age>60 years for OS (P=0.014). In conclusion, the immunologic status was closely related to lymphoma progression, and this study provides new insights into the risk stratification of patients with DLBCL.
关键词: immunologic marker diffuse large B-cell lymphoma prognosis
In vivo imaging of hematopoietic stem cell development in the zebrafish
Panpan Zhang, Feng Liu
《医学前沿(英文)》 2011年 第5卷 第3期 页码 239-247 doi: 10.1007/s11684-011-0123-0
关键词:
hematopoietic stem cell
hematopoiesis
Efficient photoelectrochemical oxidation of rhodamine B on metal electrodes without photocatalyst or
Xuejiao Wang, Xiang Feng, Jing Shang
《环境科学与工程前沿(英文)》 2018年 第12卷 第6期 doi: 10.1007/s11783-018-1061-8
•The efficient PEC degradation of RhB is realized using no photocatalyst. •The efficient PEC degradation of RhB features the low salinity. •The PEC degradation of RhB takes place on the anode and cathode simultaneously.
关键词: Energy relay structure Energy saving Photocatalyst-free and low-salinity degradation Photoelectrochemical cell
标题 作者 时间 类型 操作
Chinese expert consensus on oral drugs for the treatment of mature B-cell lymphomas (2020 edition)
期刊论文
Phase I study of CBM.CD19 chimeric antigen receptor T cell in the treatment of refractory diffuse largeB-cell lymphoma in Chinese patients
期刊论文
Neutralization against SARS-CoV-2 Delta/Omicron variants and B cell response after inactivated vaccination
期刊论文
Immunosuppressive tumor microenvironment contributes to tumor progression in diffuse large B-cell lymphoma
期刊论文
Study of recombinant human IFN-α-2b bacilli Calmette–Guerin activated killer cells and against bladdercancer cell in vitro
FAN Xiaodong, HAN Ruifa
期刊论文
characterization and comparison between CD3/CD19 bispecific and novel CD3/CD19/CD20 trispecific antibodies against B-cell
期刊论文
Inhibition of NF-kappa B can enhance Fas-mediated apoptosis in leukemia cell line HL-60
Li WANG, Shi ZHAO, Hong-Xiang WANG, Ping ZOU
期刊论文
A facile synthesis of high activity cube-like Pt/carbon composites for fuel cell application
Reza B. MOGHADDAM, Samaneh SHAHGALDI, Xianguo LI
期刊论文
Hepatitis B virus X protein upregulates tumor necrosis factor-α expression of rat mesangial cell
Hong-Zhu LU MD, Dan LIU BM, Qi-Hong FAN BM, Jian-Hua ZHOU MD,
期刊论文
Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia
Jianfeng Li, Yuting Dai, Liang Wu, Ming Zhang, Wen Ouyang, Jinyan Huang, Saijuan Chen
期刊论文
Presence of multiple abnormal immunologic markers is an independent prognostic factor of diffuse large B-cell
Yiwen Cao, Zhenhua Liu, Wen Wu, Ying Qian, Qin Shi, Rong Shen, Binshen Ouyang, Pengpeng Xu, Shu Cheng, Jin Ye, Yiming Lu, Chaofu Wang, Chengde Yang, Li Wang, Weili Zhao
期刊论文